Pustules
Pustules may be superficial or deep. Superficial pustules are categorized as either active or less active . As with papules, less active lesions are smaller, less indurated and remain for a shorter length of time than the active lesions. Pustules are seen less frequently than papules but, like papules, commonly resolve via a macular phase; however, an intermediate papular phase in either the development or regression of a pustule is not uncommon .
More often than not, the patient tends to squeeze pustules, which probably aids resolution. However, unmodified pustules last for five days - a shorter time than papules - possibly because the pustules contain many polymorphonucleocytes whose lysosomal enzymes may be more capable of resolving the inflammation than the lymphocytes which are more a feature of papules.
Deep pustules are much less common and are more frequently seen in subjects with severe acne. They usually arise from a pre-existing inflammatory papule or nodule and may persist in the pustular phase for seven days or more. Again, this type of lesion often provokes interference by the patient but with less successful outcome. Deep pustules are slightly tender. Resolution of a deep pustule usually passes through a papular phase and may take 2-6 weeks.