Topical therapy
Primary irritant dermatitis Virtually all topical treatments, if used excessively, will produce some erythema and some scaling . This 'primary irritant dermatitis' is seen especially around the side of the neck and around the eyes. The possibility of this occurrence must be explained to the patient who should be instructed that if there is any discomfort he ought to reduce the frequency of application or miss out the treatment totally for 2-3 days.
A moisturizing cream will help and, if the problem is excessive, a weak steroid ointment, such as Haelan (flurandrenolone), will prove beneficial and resolve the dermatitis in a few days. The patient can then recommence with the same preparation but, if necessary, in a lower concentration and at a decreased frequency. If the problem is recurrent, extensive patch tests are necessary to exclude an allergic dermatitis either to the active medicament or its base. This author knows of no record of a positive reaction to retinoic acid itself and the incidence of allergic dermatitis to benzoyl peroxide is of the order of 1 in 500.