Drug interactions
Most acne patients are otherwise fit and, with the possible exception of the contraceptive pill, are rarely on other medications. However, occasionally a female patient may be taking oral iron tablets for menorrhagia and a somewhat older patient may be on antacids for dyspeptic symptoms. Both these preparations will chelate with oral antibiotics; the antacids and iron can be taken after foods, the antibiotics hour before food.
There has been increasing anxiety about the possible interaction between the contraceptive pill and oral antibiotics. Dermatologists and general practitioners have given these two therapies together for fifteen years or more and there is litle evidence in the acne literature that the administration of such antibiotics reduces the efficacy of the contraceptive pill. This point will be discussed again later but an ongoing study in this author's department has failed to demonstrate an increased risk of conception in patients receiving the two therapies. Patients are told that if they develop diarrhoea while taking the antibiotics - whatever the cause - or intermenstrual spotting, then they should use other contraceptive measures. This warning is given both verbally and in writing.